Researchers estimate that compared to a male fathering a child in his early 20's - there is double the chance of the child getting schizophrenia when the father is age 40, and triple the risk of schizophrenia when the father is age 50 (though, for most people this means the risk goes from approximately 1 in 121 when a man is 29, to 1 in 47 when a man is age 50 to 54).The oldest mother to date to conceive, was 71 years, and the youngest mother, 5 years old.The girl weighed 8.69 lb (3.94 kg) and did not breath on her own.

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Aggie had been premenopausal for two years and could not produce the child herself, so she had to undergo fertilization hormone to boost her menstrual cycles so that the matrix can accommodate two to seven eggs retrieved by her daughter and fertilized in vitro with the sperm from her daughter's partner, Wilson Brown.

One of the two implanted embryos happened to appear in a lateral position in Aggie's uterus as a result of which she conceived her granddaughter through caesarean section.

Anthea Nicholas, from Gold Coast, Queensland, Australia, is believed to be the oldest primigravida having naturally conceived in Australia.

Anthea and her husband Peter were told in 2006 that they could not have children.

American actress Adrienne Barbeau gave birth to twin sons, Walker Steven and William Dalton, on March 17, 1997, at the age of 51. Senator and Vice Presidential nominee John Edwards, gave birth to son Jack in 2000 at the age of 51.

After marrying Billy Van Zandt in 1992 she started trying to have a child, tried in vitro fertilization unsuccessfully, but later became pregnant naturally. The couple decided to have more children after one of their two children—a 16-year-old son—was killed in a car accident in 1996. Edwards had also had a daughter, Emma Claire, at the age of 49.

Bershak got married at the age of 44, and after failing in conceiving naturally and adopting, she went through IVF treatment with oocyte donation and became pregnant after first attempt.

Cheryl Fillippini of Lompoc, California, gave birth to quadruplets, three girls, Rebecca, Amanda, and Sydney, and a boy, Robert, on February 20, 1997, by Caesarean section, in Santa Barbara, at the age of 50, after IVF treatment.

Japanese politician Seiko Noda gave birth to a boy in Tokyo conceived through in vitro fertilization.